منابع مشابه
ENT manifestations of Wegeners granulomatosis.
Wegeners granulomatosis is a necrotizing granulomatous vasculitis with multisystemic involvement. We present two cases of Wegener's presenting with otological manifestations as the first symptom. These symptoms are subtle and diagnosis may be easily overlooked. Hence a high index of suspicion is required. Early diagnosis and treatment goes a long way in improving the outcomes and in preventing ...
متن کاملThe Role of Anca and Anti-gbm Antibodies in Pulmonary- Renal Syndrom Due to Wegeners Granulomatosis
Pulmonary-renal syndrome (PRS) is defined as a diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis. We present a retrospective study of 22 consecutive patients with Wegeners granulomatosis (WG). Logistic regression analysis and a Wilcoxon test were included in the statistics. Survival time death risk were assessed using the Kaplan-Meier estimator and the Cox proportional haz...
متن کاملNeutrophil chemotaxis in Wegeners granulomatosis and idiopathic pulmonary fibrosis
Background: The presence of anti-neutrophil cytoplasmic antibodies (ANCA) in Wegeners granulomatosis (WG), implicate the neutrophil as a key effector cell. Previous studies have reported elevated neutrophil counts in the lung although the determinants of neutrophil chemotaxis in the WG lung are unknown. Methods: BALF cell counts, myeloperoxidase (MPO) and chemokines were measured in 27 patient...
متن کاملANCA-negative limited Wegener's granulomatosis.
A 26-year-old man presented with epistaxis, nasal obstruction and a subcutaneous swelling over the left malar region with radiological evidence of a mass in the right nasal cavity. Histology of the lesions showed necrotizing granuloma with evidence of vasculitis. There was no other systemic involvement and the patient was ANCA-negative. Excellent response to systemic steroid and cyclophosphamid...
متن کاملComparative Changes Noted in Renal Biopsies on Light Microscopy of ANCA Positive Vs ANCA Negative Serology.
OBJECTIVES Pauci-immune glomerulonephritis is the commonest cause of rapidly progressive glomerulonephritis (RPGN) which is associated with increased mortality and morbidity. More than 90% of these patients have serological presence of either antineutrophil cytoplasmic antibodies (ANCA), of cytoplamic (C) or perinuclear (P) type. "Immunofluoresence studies" exhibiting minimal or no fluorescence...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Sciences
سال: 2005
ISSN: 0019-5359
DOI: 10.4103/0019-5359.16504